Hematology Analyzers

In most laboratories, choosing a hematology analyzer comes down to three questions: how many samples are run per day, whether a 3-part or 5-part differential is required, and whether additional parameters such as CRP or ESR should run on the same instrument. Once these are settled, the shortlist narrows quickly.

Compact systems work from 10 µL of whole blood and fit into small units without a space problem. Upper-segment instruments add NRBC, immature leukocyte populations and automated rule packages to the 5-part differential, reducing the need for manual review.

Selection criteria

3-part or 5-part

3-part systems separate leukocytes into lymphocytes, monocytes and granulocytes. 5-part instruments report neutrophils, lymphocytes, monocytes, eosinophils and basophils separately, reducing manual smear review on abnormal results.

Daily test volume

A capacity of 50–60 tests per hour covers units running a few dozen patients a day. Above 80 samples per hour automated loading becomes relevant, and around 120 samples per hour conveyor automation enters the picture.

CRP or ESR integration

Running CRP simultaneously with the differential removes the need for a separate POCT device. Models with CoRA technology report ESR from the same sample and instrument as the blood count.

Sample mode and volume

Open-tube models offer flexibility at low volume; closed-tube and rack models improve sample safety and workflow speed. Micro-sampling instruments are an advantage for paediatric and difficult samples.

Reagent cost and LIS connectivity

Instrument price is only part of total cost of ownership; reagent consumption and control material spend define the annual budget. Whether LIS/HIS connectivity is included in the installation should be confirmed separately.

Comparison table

The table can be scrolled horizontally.

Products

• Yumizen H550 / H500

  Compact bench-top hematology analyzers delivering CBC and a 5-part differential. iDoubleDiff reports three immature leukocyte populations. The H500 runs open/closed tube, the H550 in rack mode.

• Yumizen H550E / H500E

  The ESR models of the Yumizen H series. Patented CoRA technology reports CBC, the 5-part differential and ESR from one sample on one instrument.

• Yumizen H500 CRP

  Compact analyzer running a simultaneous 5-part differential and CRP from whole blood. CBC and DIFF need 20 µL of sample; malaria and dengue screening flags included.

• Yumizen H2500 / H1500

  High-throughput automated hematology line. 120 samples per hour, up to 57 parameters including NRBC, automated 360° sample mixing and a validation station with ISLH rule packages.

• ABX Micros ES 60

  Compact analyzer with a 3-part differential. Works from a 10 µL whole blood micro-sample using electronic impedance for cell counting and photometry for hemoglobin. Built-in thermal printer.

• ABX Micros 60

  Entry model of the ABX Micros series; a compact bench-top analyzer with a 3-part differential. Uses the same reagent family as the ES 60.

• ABX Pentra XL 80

  Established hematology analyzer for medium and high-volume laboratories. Up to 80 samples per hour, 24 selectable QC files and a 10,000-result memory.

• ABX Pentra 60 C+

  Analyzer with a 5-part differential for medium-volume laboratories. 60 tests per hour, 12 selectable QC files and LIS connectivity.

• Pentra XLR

  Hematology analyzer designed for high-volume routine work. Up to 80 samples per hour, 36 selectable QC files and 10,000 stored results with graphs.

• Microsemi CRP LC-667G

  Analyzer combining CBC and CRP in a compact footprint. 55 tests per hour for CBC alone, 15 tests per hour when CRP runs alongside the CBC.

• Microsemi CRP LC-767G

  Delivers the same test capacity as the LC-667G in a narrower housing. Stores up to 500 patient results and 180 QC results per level.

Frequently asked questions

What is the difference between a 3-part and a 5-part hematology analyzer?

3-part analyzers separate leukocytes into three subpopulations; 5-part systems report neutrophils, lymphocytes, monocytes, eosinophils and basophils. Because they provide a more detailed differential, 5-part instruments are preferred in medium and high-volume laboratories.

Can ESR be measured on the hematology analyzer?

Yes. The Yumizen H550E and H500E models report CBC, the 5-part differential and ESR from a single sample using patented CoRA technology. The result is calibrated to the Westergren reference method; no separate ESR analyzer or additional tube is needed.

Can CRP be integrated into a hematology analyzer?

Yes. The Yumizen H500 CRP runs a simultaneous 5-part differential and CRP from whole blood. The Microsemi CRP LC-667G and LC-767G also combine CBC and CRP in one instrument, delivering 55 tests per hour for CBC alone and 15 when CRP is added.

Which analyzer suits a laboratory running 200 patients a day?

At this volume, bench-top 5-part systems with a capacity of 60–80 tests per hour are generally sufficient. If the workload is concentrated in peak hours or the STAT load is high, moving one capacity step up prevents queuing.

How is original reagent supply handled?

We supply the instrument's reagents, calibrators and control materials on a scheduled plan based on your consumption. Third-party reagents can affect measurement accuracy, quality control results and, in most cases, the instrument warranty.

Related categories

• Hemostasis systems →
• Clinical chemistry →
• Reagents and consumables →
• HORIBA Medical →